Pathways for Regulatory Innovation and Strategic Modernization (PRISM)

HHS-FDA Posted RFA-FD-26-007

Description

The Pathways for Regulatory Innovation and Strategic Modernization (PRISM) cooperative agreement is intended to advance public health by strengthening the scientific, collaborative, and operational foundations needed to modernize regulatory oversight in an increasingly complex and rapidly evolving public health landscape. As innovation in medical products, diagnostics, foods, and digital health accelerates, our nation must continuously adapt its regulatory science approaches to ensure timely access to safe, effective, and high-quality products for the American public. PRISM is designed to support this modernization by enabling forward-looking, non-regulatory collaborations that align with the Commissioner’s strategic priorities and the Administration’s broader public health goals. PRISM provides a flexible, scalable approach to patient, consumer, industry, academia, and healthcare workforce engagement to generate applied scientific knowledge, tools, and approaches that enhance regulatory predictability, efficiency, and transparency. By leveraging independent expertise and real-world insights, PRISM bridges gaps between innovation and regulation to optimize uptake of emerging technologies, evolving consumer needs, and new sources of evidence such as real-world data and real-world evidence.

Eligibility

Only the following applicant is eligible to apply for this single source funding: Reagan-Udall Foundation for the Food and Drug Administration.
Actions
View on Grants.gov
Funding Details
Award Floor
Not specified
Award Ceiling
$1,300,000.00
Total Estimated Funding
$1,300,000.00
Expected Awards
1
Key Dates
Posted
March 31, 2026
Closes
April 30, 2026
Archive Date
May 30, 2026
Agency Information
Agency Name
Food and Drug Administration
Agency Code
HHS-FDA
Funding Instrument
Other